What is nash? NASH stands for Non-Alcoholic SteatoHepatitis. It can be defined as the liver manifestation of a metabolic disorder, and is the most severe form of non-alcoholic fatty liver disease (NAFLD). NASH is closely related to the triple epidemic of obesity, pre-diabetes, and diabetes. 1 But its symptoms are often silent or non-specific to ...The conversation about nonalcoholic steatohepatitis (NASH) is heating up. Angulo P, Kleiner DE, Dam-Larsen S, et al. Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease. Gastroentrology. 2015;149 (2):389-397.Stephen John Nash OC OBC (born 7 February 1974) is a Canadian professional basketball coach and former player who most recently served as head coach of the Brooklyn Nets of the National Basketball Association (NBA). He played 18 seasons in the NBA, where he was an eight-time All-Star and a seven-time All-NBA selection.The NASH activity score, or NAS, employs the histologic features of steatosis, lobular inflammation, and ballooning. Steatosis and lobular inflammation are graded 0–3 based on severity, whereas ballooning is graded 0–2. The NAS is the unweighted sum of these collective scores.Definition & Facts. Nonalcoholic fatty liver disease (NAFLD) is a condition in which fat builds up in your liver. Nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH) are types of NAFLD. If you have NASH, you have inflammation and liver damage, along with fat in your liver. The Nash’s North Dallas location near I-75 has everything you want in a neighborhood just footsteps from your front door. Ideally located in Lake Highlands between Medical City and Presbyterian Hospital, you're close to exceptional dining establishments like Luna Grill, trendy bars like Civil Pour, and outdoor spaces like Harry S Moss Park ... There are also some less common reasons why you may get NAFLD or NASH, including…. Rapid excessive weight loss. Certain infections like hepatitis C. Medical conditions that cause your body to use or store fat improperly. Taking certain medications, such as: Glucocorticoids. Synthetic estrogens.Jun 5, 2020 · En este momento, su esposa estaba embarazada de su primer hijo. Nash renunció a su cargo como miembro de la facultad de matemáticas del MIT en la primavera de 1959 y su esposa lo hizo ingresar al Hospital McLean para el tratamiento de la esquizofrenia ese mismo año. Su hijo, John Charles Martin Nash, nació poco después. Kevin Scott Nash (born July 9, 1959) [1] is an American actor, podcaster and retired professional wrestler, currently signed to WWE under a legends contract. He is also known for his tenures with World Championship Wrestling (WCW) and Total Nonstop Action Wrestling (TNA). Nash first gained exposure in the professional wrestling industry by ... Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD). NAFLD is caused by buildup of fat in the liver. When this buildup causes inflammation and damage, it is known as NASH, which can lead to scarring of the liver. Scarring of the liver is a potentially life-threatening condition called cirrhosis. Non-alcoholic steatohepatitis, or NASH, is a liver disease in which a build-up of fat in the liver is followed by inflammation and cell damage. 1 It is rapidly becoming a leading cause of chronic liver disease 2 and a reason for liver transplantation. 3 People with NASH are also at greater risk of type 2 diabetes and cardiovascular disease. 4.NASH is a chronic liver disease characterized by liver cell injury (hepatocellular ballooning) and inflammation as a result of fatty accumulation (steatosis) seen in at least 5% of hepatocytes. This leads to liver scarring and the development of fibrosis (scored F0 to F4). As fibrosis worsens, liver-related morbidity (including cirrhosis and ...fatty liver foundation to mark international nash day with three interactive programs offering information, inspiration, and support for people at-risk of or living with nafld/nash; fatty liver foundation’s annual national survey aims to reshape nafld/nash care in the u.s. Lucy Nash works for the Bureau of Investigative Journalism’s Enablers project, which investigates how money and reputations are laundered in the UK.NASH is the more serious form of non-alcoholic fatty liver disease (NAFLD), which is the most common liver disease in Western industrialized nations, affecting one out of four adults. NASH and NAFLD are especially prevalent in, but not limited to, people with metabolic disorders such as type 2 diabetes and obesity.Search Nash family obituaries and memoriams on Legacy.com. There are 13158 obituaries and memoriams for the surname Nash.A diet for NASH/cirrhosis patients is designed to minimize the work the liver must do and reduce inflammation. The most important element is the heavy reliance on extra virgin olive oil as the source of unsaturated dietary fat.There are also some less common reasons why you may get NAFLD or NASH, including…. Rapid excessive weight loss. Certain infections like hepatitis C. Medical conditions that cause your body to use or store fat improperly. Taking certain medications, such as: Glucocorticoids. Synthetic estrogens.Nov 13, 2020 · Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease that is characterized by the accumulation of fat (steatosis), hepatocyte damage, and inflammation. It can ... As NASH progresses and liver damage gets worse, you may start to have symptoms such as: Fatigue (feeling tired all the time). Weight loss for no clear reason. General weakness. An ache in the upper right part of your belly. It may take many years for NASH to become severe enough to cause symptoms.NASH: Progression of a potentially life-threatening disease Non-alcoholic fatty liver disease (NAFLD) is a collective term used to describe a group of conditions where there is an abnormal accumulation of fat in the liver in those who drink little to no alcohol. Supplemental Materials. This AACE guideline provides evidence-based recommendations regarding the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) to endocrinologists, primary care clinicians, health care professionals, and other stakeholders. It was co-sponsored by AASLD. Non-alcoholic steatohepatitis, or NASH, is a liver disease in which a build-up of fat in the liver is followed by inflammation and cell damage. 1 It is rapidly becoming a leading cause of chronic liver disease 2 and a reason for liver transplantation. 3 People with NASH are also at greater risk of type 2 diabetes and cardiovascular disease. 4.Jan 6, 2021 · NASH is, therefore, a progressive subtype of NAFLD that can result in cirrhosis, hepatocellular carcinoma and liver-related mortality. Importantly, hepatic fibrosis is the only histologic feature of NASH independently associated with long-term overall mortality, liver transplantation and liver-related mortality ( 5 ). Non-alcoholic steatohepatitis (NASH) is a fast-growing and highly prevalent threat to health, set to become a major cause of liver cancer and transplant. 1 NASH, an advanced form of non-alcoholic fatty liver disease (NAFLD), is strongly linked to obesity and metabolic disorders. There are no licensed therapies for NASH, despite its prevalence ...2 years. The _ga cookie, installed by Google Analytics, calculates visitor, session and campaign data and also keeps track of site usage for the site's analytics report. The cookie stores information anonymously and assigns a randomly generated number to recognize unique visitors. _ga_77PP4X82CT.Nov 2, 2022 · NASH is a type of NAFLD that’s often associated with metabolic disorders. It’s characterized by excess fat accumulation, as well as inflammation that can potentially damage healthy liver tissues. Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Treatment. The first line of treatment for NAFLD and NASH is weight loss, done through a combination of calorie reduction, exercise, and healthy eating. Weight loss can reduce fat and inflammation in the liver. The following lifestyle changes are important in managing your disease.NASH. NASH is the form of NAFLD in which you have inflammation of the liver and liver damage, in addition to fat in your liver. The inflammation and liver damage of NASH can cause fibrosis, or scarring, of the liver. NASH may lead to cirrhosis, in which the liver is scarred and permanently damaged. Cirrhosis can lead to liver cancer.Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease that is characterized by the accumulation of fat (steatosis), hepatocyte damage, and inflammation. It can ...Apr 4, 2022 · NASH is also characterized as excess of nutrition and energy, which exhibits exacerbated accumulation of fats in the liver and other peripheral tissues. Mitochondria is the power generator of ... Nonalcoholic steatohepatitis, or NASH, is the most severe form of nonalcoholic fatty liver disease (NAFLD), a condition in which the liver builds up excessive fat deposits. 1. The liver is part of the digestive system. The organ helps break down food, store energy, filter waste products, and remove toxins. 1 Even healthy livers contain some fat ... Analytical methods: The NIS4 NASH Diagnostic Test is an In Vitro Diagnostic Multivariate Assay (IVDMIA) Test that calculates a score based on the quantification of four individual analytes: a.The Nash’s North Dallas location near I-75 has everything you want in a neighborhood just footsteps from your front door. Ideally located in Lake Highlands between Medical City and Presbyterian Hospital, you're close to exceptional dining establishments like Luna Grill, trendy bars like Civil Pour, and outdoor spaces like Harry S Moss Park ... Usually, nonalcoholic fatty liver disease (NAFLD)—including nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH)—is a silent disease with few or no symptoms. You may not have symptoms even if you develop cirrhosis due to NASH. A diet for NASH/cirrhosis patients is designed to minimize the work the liver must do and reduce inflammation. The most important element is the heavy reliance on extra virgin olive oil as the source of unsaturated dietary fat.Fruits can be a part of a NASH diet in moderation. Whole fruits can provide many nutrients and vitamins to the body and make for a suitable snack or dessert. Fruits may include: citrus fruits ...Today, NASH diagnosis is often formally established using a liver biopsy. But this invasive procedure, while currently the gold standard, can be costly, uncomfortable, and potentially risky for patients. 4 Additionally, the number of specialists available to perform and interpret a biopsy is very limited compared to the number of patients ...fatty liver foundation to mark international nash day with three interactive programs offering information, inspiration, and support for people at-risk of or living with nafld/nash; fatty liver foundation’s annual national survey aims to reshape nafld/nash care in the u.s. Browse by Disease. Browse the GARD list of rare diseases to find topics of interest. This list includes both the main, and any alternate names for each disease. Inclusion on this list does not serve as official recognition by the NIH that a disease is rare. Showing 1 - 10 of 5853. New drugs for NASH. 2021 Jun;41 Suppl 1:112-118. doi: 10.1111/liv.14844. Non-alcoholic steatohepatitis (NASH) is a result of inflammation and hepatocyte injury in the presence of hepatic steatosis which can progress to cirrhosis. NASH is the most rapidly growing aetiology for liver failure and indication for liver transplantation in the United ...None of the drugs have been approved by the Food and Drug Administration for treating biopsy-proven non-alcoholic steatohepatitis (NASH). Vitamin E and pioglitazone have been extensively used in treatment of biopsy-proven nondiabetic NASH patients. Although some amelioration of inflammation has been seen, these drugs did not improve the ...If you have NASH and severe scarring of your liver, you may have some of the following signs and symptoms of cirrhosis: Intense itching. A swollen belly ( ascites) Bruising and bleeding easily. Yellowing of the skin and eyes ( jaundice) Spider-like blood vessels just beneath your skin’s surface. Behavior changes, slurred speech, and confusion ...NASH is a condition caused by the presence of fat in the liver. It is a subset of non-alcoholic fatty liver disease. Over time, the fat in the liver can lead to liver inflammation, the end stage of which we call NASH. The liver enlarges as it accumulates fat.John Nash, in full John Forbes Nash, Jr., (born June 13, 1928, Bluefield, West Virginia, U.S.—died May 23, 2015, near Monroe Township, New Jersey), American mathematician who was awarded the 1994 Nobel Prize for Economics for his landmark work, first begun in the 1950s, on the mathematics of game theory.Stephen John Nash OC OBC (born 7 February 1974) is a Canadian professional basketball coach and former player who most recently served as head coach of the Brooklyn Nets of the National Basketball Association (NBA). He played 18 seasons in the NBA, where he was an eight-time All-Star and a seven-time All-NBA selection.Today, NASH diagnosis is often formally established using a liver biopsy. But this invasive procedure, while currently the gold standard, can be costly, uncomfortable, and potentially risky for patients. 4 Additionally, the number of specialists available to perform and interpret a biopsy is very limited compared to the number of patients ...Jan 6, 2021 · NASH is, therefore, a progressive subtype of NAFLD that can result in cirrhosis, hepatocellular carcinoma and liver-related mortality. Importantly, hepatic fibrosis is the only histologic feature of NASH independently associated with long-term overall mortality, liver transplantation and liver-related mortality ( 5 ). Nov 3, 2016 · Choose low fat or fat free milk, yogurt and cheese. Pass on sugar-sweetened dairy products such as yogurt or flavored milks or sweetened milk alternatives. This strawberry banana milkshake uses soy milk and fresh fruit to satisfy your sweet tooth. Healthy fats: Eat healthy fats daily, like walnuts, hazelnuts and almonds. Nash is a cybernetically enhanced shark creature who is the champion of Barin. In the beginning of the cutscene, Nash is seen boxing with himself saying "Put 'em up, put 'em up!" He becomes antsy and begins yelling at Velo to start the race immediately but backs down when Velo starts to lose his temper with him. NASH is a type of NAFLD, which may be the most common chronic liver disease in industrialized nations, including the U.S. As many as 25% of U.S. adults may have NAFLD.NASH is a type of NAFLD that’s often associated with metabolic disorders. It’s characterized by excess fat accumulation, as well as inflammation that can potentially damage healthy liver tissues.New drugs for NASH. 2021 Jun;41 Suppl 1:112-118. doi: 10.1111/liv.14844. Non-alcoholic steatohepatitis (NASH) is a result of inflammation and hepatocyte injury in the presence of hepatic steatosis which can progress to cirrhosis. NASH is the most rapidly growing aetiology for liver failure and indication for liver transplantation in the United ...As NASH progresses and liver damage gets worse, you may start to have symptoms such as: Fatigue (feeling tired all the time). Weight loss for no clear reason. General weakness. An ache in the upper right part of your belly. It may take many years for NASH to become severe enough to cause symptoms.Nonalcoholic steatohepatitis (NASH) is liver inflammation and damage caused by a buildup of fat in the liver. It is part of a group of conditions called nonalcoholic fatty liver disease. You may be told you have a "fatty liver." Many people have a buildup of fat in the liver, and for most people it causes no symptoms and no problems.This Access Page provides Nash County Employees quick entrance to the Intranet, email and remote access log-ins. Access to this system is granted to authorized users only. Unauthorized access is prohibited. Provides 24/7 tech support of remote PCs, Macs, and smartphones enabling quick access, and repair of remote devices.Browse by Disease. Browse the GARD list of rare diseases to find topics of interest. This list includes both the main, and any alternate names for each disease. Inclusion on this list does not serve as official recognition by the NIH that a disease is rare. Showing 1 - 10 of 5853. NASH is a type of NAFLD, which may be the most common chronic liver disease in industrialized nations, including the U.S. As many as 25% of U.S. adults may have NAFLD.Non-alcoholic steatohepatitis (NASH) is a fast-growing and highly prevalent threat to health, set to become a major cause of liver cancer and transplant. 1 NASH, an advanced form of non-alcoholic fatty liver disease (NAFLD), is strongly linked to obesity and metabolic disorders. There are no licensed therapies for NASH, despite its prevalence ...Nash County is a thriving community located just east of Raleigh that is the perfect home for young families. We have excellent employment opportunities and a great quality of life that you can't get just anywhere. Check out the brew mill scene in Rocky Mount, live a little at one of our small town festivals, or get lost in nature with miles ...Jan 21, 2022 · NASH is associated with an increased risk of cardiovascular disease and Type 2 diabetes mellitus. There are still no U.S. FDA approved drugs or biological treatments for NASH or related liver ... Non-alcoholic steatohepatitis, or NASH, is a liver disease in which a build-up of fat in the liver is followed by inflammation and cell damage. 1 It is rapidly becoming a leading cause of chronic liver disease 2 and a reason for liver transplantation. 3 People with NASH are also at greater risk of type 2 diabetes and cardiovascular disease. 4.The NASH activity score, or NAS, employs the histologic features of steatosis, lobular inflammation, and ballooning. Steatosis and lobular inflammation are graded 0–3 based on severity, whereas ballooning is graded 0–2. The NAS is the unweighted sum of these collective scores.Nash offers unparalleled expertise in the design and manufacture of systems to meet your specific process needs. Our systems are ready for operation, easy to integrate into process automation, help minimize installation and operating costs, and meet the rigors of the most demanding applications. Metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis or NASH) is a type of fatty liver disease. It often develops due to a metabolic disorder, such as obesity or diabetes, resulting in a toxic buildup of fat in the liver. It is the most severe form of metabolic dysfunction-associated steatotic ...Jul 19, 2023 · Metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis or NASH) is a type of fatty liver disease. It often develops due to a metabolic disorder, such as obesity or diabetes, resulting in a toxic buildup of fat in the liver. It is the most severe form of metabolic dysfunction-associated steatotic ... Definition & Facts. Nonalcoholic fatty liver disease (NAFLD) is a condition in which fat builds up in your liver. Nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH) are types of NAFLD. If you have NASH, you have inflammation and liver damage, along with fat in your liver.The Nash 600 is an automobile that was manufactured by the Nash-Kelvinator Corporation of Kenosha, Wisconsin for the 1941 through 1949 model years, after which the car was renamed the Nash Statesman. The Nash 600 was positioned in the low-priced market segment. The '600' name comes from the car's ability to go 600 miles on one tank of gasoline. Apr 4, 2022 · NASH is also characterized as excess of nutrition and energy, which exhibits exacerbated accumulation of fats in the liver and other peripheral tissues. Mitochondria is the power generator of ... The NASH activity score, or NAS, employs the histologic features of steatosis, lobular inflammation, and ballooning. Steatosis and lobular inflammation are graded 0–3 based on severity, whereas ballooning is graded 0–2. The NAS is the unweighted sum of these collective scores.NAFLD and NASH. Fuelled by increasing obesity rates, NAFLD has emerged as a leading global cause of chronic liver disease in the past few decades. Despite growing prevalence, the factors ...Search Nash family obituaries and memoriams on Legacy.com. There are 13158 obituaries and memoriams for the surname Nash.Jan 14, 2022 · Fruits can be a part of a NASH diet in moderation. Whole fruits can provide many nutrients and vitamins to the body and make for a suitable snack or dessert. Fruits may include: citrus fruits ... As NASH progresses and liver damage gets worse, you may start to have symptoms such as: Fatigue (feeling tired all the time). Weight loss for no clear reason. General weakness. An ache in the upper right part of your belly. It may take many years for NASH to become severe enough to cause symptoms. Non-alcoholic steatohepatitis (NASH) is a fast-growing and highly prevalent threat to health, set to become a major cause of liver cancer and transplant. 1 NASH, an advanced form of non-alcoholic fatty liver disease (NAFLD), is strongly linked to obesity and metabolic disorders. There are no licensed therapies for NASH, despite its prevalence ... Aug 18, 2023 · Nonalcoholic Steatohepatitis (NASH): Symptoms. Usually NAFLD and NASH do not cause symptoms. If you do have symptoms, you may feel tired or have pain in the upper right side of your abdomen, where your liver is. Learn more about recognizing the signs and symptoms of NASH. Non-alcoholic steatohepatitis, or NASH, is a liver disease in which a build-up of fat in the liver is followed by inflammation and cell damage. 1 It is rapidly becoming a leading cause of chronic liver disease 2 and a reason for liver transplantation. 3 People with NASH are also at greater risk of type 2 diabetes and cardiovascular disease. 4.Volunteering at The Nash is the perfect way to enjoy jazz and help promote the music we all love—and to have […] + 1 More 2 events, 24 2 events, 24 3:00 pm ...Nonalcoholic, fatty liver disease (NAFLD) is defined as the ectopic accumulation of fat in the liver (hepatic steatosis) when no other causes of secondary liver fat accumulation are present. Although, minor deposition of fat can occur in the liver of healthy adults, deposition of fat in at least 5% of hepatocytes is considered pathologic. NAFLD includes both nonalcoholic fatty liver (NAFL) and ...
Definition & Facts. Nonalcoholic fatty liver disease (NAFLD) is a condition in which fat builds up in your liver. Nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH) are types of NAFLD. If you have NASH, you have inflammation and liver damage, along with fat in your liver. . Atandt putages
Fruits can be a part of a NASH diet in moderation. Whole fruits can provide many nutrients and vitamins to the body and make for a suitable snack or dessert. Fruits may include: citrus fruits ...Non-alcoholic steatohepatitis, or NASH, is a liver disease in which a build-up of fat in the liver is followed by inflammation and cell damage. 1 It is rapidly becoming a leading cause of chronic liver disease 2 and a reason for liver transplantation. 3 People with NASH are also at greater risk of type 2 diabetes and cardiovascular disease. 4.Prof. Stephen Harrison (USA) reviews current and future therapies for Non-Alcoholic Steatohepatitis (NASH). After a focus on the pathogenesis of NASH and the different pathways on how underlying steatohepatitis is developed, he presents his expert perspective on how patient outcomes can be improved. Prof. Stephen Harrison.3. Carol Denise Betts (née Ensley; born February 23, 1970), [1] known professionally as Niecy Nash ( / ˈniːsi / ), is an American actress, best known for her performances on television. Her acting career began in the late 1990s, with numerous guest appearances on television shows. She garnered further recognition for her portrayal of Deputy ... Analytical methods: The NIS4 NASH Diagnostic Test is an In Vitro Diagnostic Multivariate Assay (IVDMIA) Test that calculates a score based on the quantification of four individual analytes: a.Supplemental Materials. This AACE guideline provides evidence-based recommendations regarding the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) to endocrinologists, primary care clinicians, health care professionals, and other stakeholders. It was co-sponsored by AASLD.Aug 18, 2023 · Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Treatment. The first line of treatment for NAFLD and NASH is weight loss, done through a combination of calorie reduction, exercise, and healthy eating. Weight loss can reduce fat and inflammation in the liver. The following lifestyle changes are important in managing your disease. 1964 Nash Rambler. 1964 Rambler 770 Classic The Rambler Classic is an intermediate sized automobile that was built and ... $49,000. Dealership.The Nash’s North Dallas location near I-75 has everything you want in a neighborhood just footsteps from your front door. Ideally located in Lake Highlands between Medical City and Presbyterian Hospital, you're close to exceptional dining establishments like Luna Grill, trendy bars like Civil Pour, and outdoor spaces like Harry S Moss Park ... NASH. NASH is the form of NAFLD in which you have inflammation of the liver and liver damage, in addition to fat in your liver. The inflammation and liver damage of NASH can cause fibrosis, or scarring, of the liver. NASH may lead to cirrhosis, in which the liver is scarred and permanently damaged. Cirrhosis can lead to liver cancer.During a physical exam, a doctor usually examines your body and checks your weight and height to calculate your body mass index. Your doctor will look for signs of NAFL or NASH, such as. an enlarged liver. signs of insulin resistance, such as darkened skin patches over your knuckles, elbows, and knees. signs of cirrhosis, such as an enlarged ... NASH and Genetics. Genetics seem to contribute to NAFLD and NASH. Research has identified gene changes that might play a role, including a certain variation in the PNPLA3 gene. 8 This gene gives cells instructions for making adiponutrin, a protein found in liver cells and fat cells. 9 Scientists believe that a particular change in the PNPLA3 gene could cause increased fat production and ...New drugs for NASH. 2021 Jun;41 Suppl 1:112-118. doi: 10.1111/liv.14844. Non-alcoholic steatohepatitis (NASH) is a result of inflammation and hepatocyte injury in the presence of hepatic steatosis which can progress to cirrhosis. NASH is the most rapidly growing aetiology for liver failure and indication for liver transplantation in the United ...Nov 3, 2016 · Choose low fat or fat free milk, yogurt and cheese. Pass on sugar-sweetened dairy products such as yogurt or flavored milks or sweetened milk alternatives. This strawberry banana milkshake uses soy milk and fresh fruit to satisfy your sweet tooth. Healthy fats: Eat healthy fats daily, like walnuts, hazelnuts and almonds. Obesity, diabetes, insulin resistance, sedentary lifestyle, and Western diet are the key factors underlying non-alcoholic fatty liver disease (NAFLD), one of the most common liver diseases in developed countries. In many cases, NAFLD further progresses to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and to hepatocellular carcinoma. The hepatic lipotoxicity and non-liver factors ....